Atypical fibroxanthoma (AFX) is a tumor that occurs primarily in older individuals after the skin of the head and neck has been damaged significantly by sun exposure and/or therapeutic radiation.

Abstract. Introduction: Atypical fibroxanthoma (AFX) is a rare cutaneous tumor without a completely defined histogenesis which frequently develops on head and neck of elderly people. Its diagnosis is histological, of exclusion with other tumors with identical morphology. Despite its classical benign behavior some rare cases reporting distant metastasis classified it on intermediate malignancy.

AFX appears clinically as a discrete red or pink nodule or papule …. Atypical fibroxanthoma (AFX) is a dermal Atypical fibroxanthoma (AFX) is a rare, low-grade dermal sarcoma. We analyzed our files from January 2001 to January 2020 for AFX. Clinical parameters, histopathology, treatment and outcome have been investigated. We identified 87 patients (mean age of 80.0 ± 8.4 years) with 105 confirmed tumors. Of these patients 86.2% were males.

However, varying degrees of subcutaneous involvement can lead to a more aggressive course and rare metastases. Atypical fibroxanthoma is a low-grade sarcoma of the skin. (See also Overview of Skin Cancer.) Atypical fibroxanthomas are rare among nonmelanoma skin cancers. They most commonly occur on the head and neck of older patients. They appear similar to other nonmelanoma skin cancers, as nonhealing or tender pink-red skin papules or nodules. Histologic Findings. The pathologic appearance of atypical fibroxanthoma (AFX) belies the usually excellent prognosis.

Pathology.

Atypical fibroxanthomas might be detected as a nodular skin lesion of some millimeters up to some centimeters on ultrasound, CT or MRI. After administration of a contrast agent, it has been described to show enhancement. Treatment and prognosis. Atypical fibroxanthomas are surgically removed and have a good prognosis.

Atypical fibroxanthoma is a skin cancer often seen in sun-exposed areas. It resembles squamous cell carcinoma or basal cell carcinoma because of the presence of a pink papule or erosion.

Atypical fibroxanthoma (AFX) is a nodular dermal ulcerative lesion with a favorable prognosis. AFX most commonly occurs on sun-exposed skin in elderly individuals. AFX is characterized by its assoc

Treatment and prognosis.

Atypical fibroxanthoma (AFX) is a dermal Atypical fibroxanthoma (AFX) is a rare, low-grade dermal sarcoma.
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Making a diagnosis of AFX is challenging, and it is important to differentiate it from squamous Background: Atypical fibroxanthoma (AFX) is an uncommon, rapidly growing cutaneous neoplasm of uncertain histogenesis. Thus far, there are no guidelines for diagnosis and therapy of this tumor. BACKGROUND Atypical fibroxanthoma (AFX) is an uncommon superficial fibrohistiocytic tumor.
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Atypical Fibroxanthoma tumors appear as well-defined and small nodules, which are mostly painless. They form on the head and neck area, in most cases, and may ulcerate and bleed; Complete excision by surgery is curative and the prognosis of Atypical Fibroxanthoma is usually excellent. However, occasionally the tumors are known to recur

Atypical fibroxanthoma From Wikipedia, the free encyclopedia Atypical fibroxanthoma of the skin is a low-grade malignancy related to malignant fibrous histiocytoma, which it resembles histologically. 2020-10-14 · Atypical fibroxanthoma (AFX) is a tumor that occurs primarily in older individuals after the skin of the head and neck has been damaged significantly by sun exposure and/or therapeutic radiation. Clinically, lesions usually are suggestive of malignancy because they arise rapidly (over just a few weeks or months) in skin in which other skin ca ATYPICAL FIBROXANTHOMA OF THE SKIN A Clinicopathologic Study of 140 Cases DAVID F. FRETZIN, MD," AND ELSON B. HELWIC, MD+ In an attempt to further understand the nature of atypical fibroxanthoma of the skin, 140 lesions were subjected to clinical, histologic, and histochemical studies.

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This video discusses the basic workup of a pleomorphic malignant cutaneous spindle cell tumor. The main differential diagnosis includes spindle cell melanoma

Here is a short video of Mayo Clinic dermatologic surgeon, Dr. Jerry Brewer discussing AFx. He tells us about the risk factors, diagnosis and treatment of this rare form of skin cancer. Atypical fibroxanthoma (AFX) is a dermal spindle-cell tumour that typically occurs on the head and neck of sun damaged older people. The tumour-like growth should be considered a type of skin cancer but it may behave in a benign fashion.

AFX is one of the more recognizable skin cancers that can affect the body. It is characterized by the sudden development of a red or pink bump, nodule, or dome shaped ulcer. It is typically found on the head and neck of elderly patients with skin damage from over exposure to UV rays.

Atypical Fibroxanthoma - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical Professional Version. Atypical fibroxanthoma (AFX) is a nodular dermal ulcerative lesion with a favorable prognosis. AFX most commonly occurs on sun-exposed skin in elderly individuals. AFX is characterized by its association with ultraviolet radiation, not only from a clinical aspect, but also from a molecular aspect.

Fortunately, atypical fibroxanthoma rarely metastasizes and recurs in only 6% to 10% of cases 6). Atypical fibroxanthoma (AFX) is a dermal spindle-cell sarcoma that is considered a superficial and clinically benign presentation of pleomorphic dermal sarcoma, malignant fibrous histiocytoma, and undifferentiated pleomorphic sarcoma. AFX appears clinically as a discrete red or pink nodule or papule …. Atypical fibroxanthoma (AFX) is a dermal Atypical fibroxanthoma (AFX) is an uncommon, pleomorphic, spindle cell cutaneous malignancy that most commonly presents as a solitary red or pink papule or nodule on the head or neck .